Vzpomínka na Stanislava HavelkuInformations

J. Blahoš

Clin Osteol 2004; 9(4): 115

Bone mineral density in relation to oral contraceptive useArticles

M. Sojáková, J. Payer, M. Borovský, Z. Killinger, P. Hrúziková, E. Stenová, P. Ondrejka

Clin Osteol 2004; 9(4): 116-120

Background: The impact of oral contraceptive use on bone mineral density (BMD) and risk of osteoporotic fractures remains unclear. Positive and negative effects on BMD have been described in several retrospective studies with postmenopausal women and prospective studies with perimenopausal women. However, there is a paucity of prospective studies evaluating the role of contraceptive pills on bone in young women with childbearing potential. Aim of the study: Pilot, cross-sectional study in healthy young women has been designed to investigate: 1) the impact of oral contraceptive use on BMD at lumbar spine and total femur, 2) the correlation of physiological...

The place of kinesiotherapy in the management of osteoporosisArticles

E. Ďurišová, J. Zvarka

Clin Osteol 2004; 9(4): 121-126

Aims: Assesment of the efficiency of regular exercise as part of the comprehensive appoach to the management of female patients with postmenopau­ sal osteoporosis. Methods: Eighty-nine postmenopausal age women were included in the study, showing predominantly sedentary lifestyles and presenting with densitometrically verified osteoporosis according to the WHO criteria. None of the women in the group had osteoporotic fracture in her medical history. The patients were randomly assigned to two groups (Exercise-A and Control-K). The patients of both groups were taking: 60 mg raloxifene, 1 000 mg calcium, 800 IU vitamin D daily. The observation period was...

Importance of sexual steroids for integrity of the skeletonReview articles

I. Žofková, K. Zajíčková

Clin Osteol 2004; 9(4): 127-129

Importace of sexual steroids for the skeleton exceeds that of other classic calciotropic systems such as parathyroid hormone - 1,25(OH2 vitamin D or somatotropin - IGF-I. Estrogen acts at several levels of bone remodeling and it is a potent predictor of bone mass in women as well as in men. Ex­ traordinary importance of estrogen for integrity of male and female skeleton is probably connected with development of specific nuclear receptors ear­ ly in the evolution, long ago before androgen receptors. Authors observed association between circulating precursors of sex-steroids and some candi­ date genes for bone mass. This association strengthens the hypothesis...

The dominant influences accelerating or retarding the changes in cortical densityReview articles

M. Petrtýl, J. Danešová

Clin Osteol 2004; 9(4): 130-135

Limit cycles of bone remodelling are regulated biomechanically and biochemically (genetically). The speeds of biochemical reactions (i.e. the speeds of intense metabolic processes) depend on the volume changes of molecular mixtures and on the stress changes in a bone element. Processes of densi­ ty depend on both the dominant volume changes of molecular mixtures and stress changes. The resultant speed of the j-th biochemical reaction, which forms part of biochemical (metabolic) processes in the bone tissue (in the remodelling limit cycle) is dependent on the product of speeds of the bio­ chemical reaction initiated biochemically (resp. genetically)...

Abstracts from abroadLiterature

Clin Osteol 2004; 9(4): 136

Congress announcementsInformations

Clin Osteol 2004; 9(4): 137

Minutes of the Committee meeting of the Society for Metabolic Skeletal DiseasesInformations

Clin Osteol 2004; 9(4): 138

Informations from IOFInformations

Clin Osteol 2004; 9(4): 139

Prof. MUDr. Stanislav Havelka, CSc.Personalia

Clin Osteol 2004; 9(4): 140

In memory of Professor Stan Havelka, MD, PhD 115, 140,Personalia

Clin Osteol 2004; 9(4): 141