Clin Osteol 2020; 25(2): 99-102

Osteolytic deposits of the pelvis leading to the diagnosis of primary hyperparathyreosis: case reportCase reports

Jr Raška Ivan1, Rašková Mária1, Včelák Josef2, Junková Kristýna2,3
1 III. interní klinika - endokrinologie a metabolismu 1. LF UK a VFN v Praze
2 Endokrinologický ústav v Praze
3 Ústav biologie a lékařské genetiky 1. LF UK a VFN v Praze

Primary hyperparatyroidism (PHPT) is a common endocrine disease and represents the most common cause of hypercalcemia. Thanks to modern diagnostic and laboratory approaches that allow us to diagnose and treat asympto­matic and mild forms of PHPT, the number of patients with clinically symptomatic PHPT decreases. The case report deals with the case of a 30 year old woman who underwent medical examination due to renal colic. Nephrolithiasis and multiple osteolytic lesions in the pelvic area were found on CT. A differential diagnostic examination was initiated considering a hematological malignancy that was excluded. After calcium-phosphate metabolism examination clinically symptomatic PHPT diagnosis was set.

Keywords: primary hyperparathyroidism; brown tumor; osteolytic leasons

Received: July 13, 2020; Accepted: July 16, 2020; Published: December 11, 2020  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Raška Ivan J, Rašková M, Včelák J, Junková K. Osteolytic deposits of the pelvis leading to the diagnosis of primary hyperparathyreosis: case report. Clinical Osteology. 2020;25(2):99-102.
Download citation

References

  1. Yu N, Donnan PT, Murphy JM et al. Epidemiology of Primary Hyperparathyroidism in Tayside, Scotland, UK. Clin Endocrinol (Oxf) 2009; 71(4): 485-493. Dostupné z DOI: <http://dx.doi.org/10.1111/j.1365-2265.2008.03520.x>. Go to original source...
  2. Adami S, Marcocci C, Gatti D. Epidemiology of Primary Hyperparathyroidism in Europe. J Bone Miner Res 2002; 17(Suppl 2): N18-N23.
  3. Bilezikian JP, Bandeira L, Khan A et al. Hyperparathyroidism. Lancet 2018; 391(10116): 168-178. Dostupné z DOI: <http://dx.doi.org/10.1016/S0140-6736(17)31430-7>. Go to original source...
  4. Shane E. Clinical review 122: Parathyroid Carcinoma. J Clin Endocrinol Metab 2001; 86(2): 485-493. Dostupné z DOI: <http://dx.doi.org/10.1210/jcem.86.2.7207>. Go to original source...
  5. Rosa J, Raska I Jr, Wichterle D et al. Pulse Wave Velocity in Primary Hyperparathyroidism and Effect of Surgical Therapy Hypertens Res 2011; 34(3): 296-300. Dostupné z DOI: <http://dx.doi.org/10.1038/hr.2010.232>. Go to original source...
  6. Pepe J, Cipriani C, Sonato C et al. Cardiovascular manifestations of primary hyperparathyroidism: a narrative review. Eur J Endocrinol 2017; 177(6): R297-R308. Dostupné z DOI: <http://dx.doi.org/10.1530/EJE-17-0485>. Go to original source...
  7. Silverberg SJ, Bilezikian JP. Evaluation and management of primary hyperparathyroidism. J Clin Endocrinol Metab 1996 : 81(6): 2036-2040. Dostupné z DOI: <http://dx.doi.org/10.1210/jcem.81.6.8964825>. Go to original source...
  8. Bilezikian JP, Brandi ML, Rubin SJ et al. Primary hyperparathyroidism: new concepts in clinical, densitometric and biochemical features. J Intern Med 2005; 257(1): 6-17. Dostupné z DOI: <http://dx.doi.org/10.1111/j.1365-2796.2004.01422.x>. Go to original source...
  9. Can O, Boynueğri B, Gökçe Özgür Can O et al. Brown Tumors: A Case Report and Review of the Literature 2016. Case Rep Nephrol Dial 2016; 6(1): 46-52. Dostupné z DOI: <http://dx.doi.org/10.1159/000444703>. Go to original source...
  10. Bandeira F, Cusano NE, Silva BC et al. Bone disease in primary hyperparathyroidism. Arq Bras Endocrinol Metabol 2014; 58(5): 553-561. Dostupné z DOI: <http://dx.doi.org/10.1590/0004-2730000003381>. Go to original source...
  11. Ullah E, Ahmad M, Ali SA et al. Primary hyperparathyroidism having multiple Brown tumors mimicking malignancy. Indian J Endocrinol Metab 2012; 16(6): 1040-1042. Dostupné z DOI: <http://dx.doi.org/10.4103/2230-8210.103037>. Go to original source...
  12. Misiorowski W, Czajka-Oraniec I, Kochman M et al. Osteitis Fibrosa Cystica-A Forgotten Radiological Feature of Primary Hyperparathyroidism Endocrine 2017; 58(2): 380-385. Dostupné z DOI: <http://dx.doi.org/10.1007/s12020-017-1414-2>. Go to original source...
  13. Panagopoulos A, Tatani I, Kourea HP et al. Osteolytic lesions (brown tumors) of primary hyperparathyroidism misdiagnosed as multifocal giant cell tumor of the distal ulna and radius: a case report. J Med Case Rep 2018; 12(1): 176. Dostupné z DOI: <http://dx.doi.org/10.1186/s13256-018-1723-y>. Go to original source...




Clinical Osteology

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.