Clin Osteol 2012; 17(1): 3-7

Vitamin D receptor gene BsmI polymorphism and bone phenotypes in the region of Central MoraviaOriginal contributions

P. Hrdý, P. Novosad, P. Fojtík, P. Horák, R. Richterová

In recent years, results of studies in exposed families or association projects have supported the significant role of heredity in the etio­ logy of osteoporosis. In the description of clinical manifestations of osteoporosis, various surrogate bone phenotypes have been used, including bone mineral density of the lumbar spine and femur, hip geometry, microarchitecture, bone turnover markers and skeletal fractures. The relationship between BsmI polymorphism of the vitamin D receptor gene and bone phenotypes has been analyzed to track one of possible link between heredity and clinical manifesta

Keywords: bone phenotype, vitamin D receptor, genetic polymorphism

Published: June 11, 2012  Show citation

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Hrdý P, Novosad P, Fojtík P, Horák P, Richterová R. Vitamin D receptor gene BsmI polymorphism and bone phenotypes in the region of Central Moravia. Osteologický bulletin. 2012;17(1):3-7.
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