Clin Osteol 2009; 14(2): 41-48

Diagnosing osteoporosis in childrenReview articles

Z. Šumník, O. Souček

Aetiopathogenesis of osteoporosis is significantly different in children than in adults. Children most commonly present with seconda­ ry osteoporosis due to chronic diseases and/or their treatment. In children, low bone density is diagnosed following DXA findings and fracture history. When considering potential therapy, in addition to bone density parameters and history, the expected development of bone quality or strength should be individually assessed, with respect to the activity of the underlying disease and its therapy. DXA findings should always be interpreted with respect to anthropometric parameters, in particular the height and stage of puberty, to avo­ id false overdiagnosis of osteoporosis in children short for their age. Methods based on the assessment of volumetric bone density pro­ vide a new perspective on measuring bone strength in children. As yet, however, no studies are available which quantify the risk of fractures depending on BMC and BMD changes measured by CT densitometry. The methods used in the future will be probably tho­ se capable of assessing bone microarchitecture as well, i.e. micro-CT or micro-MRI. The article summa gnosing bone strength in children and provides an overview of methods available in clinical practice.

Keywords: bone density, bone strength, DXA, CT densitometry, children

Published: December 11, 2009  Show citation

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Šumník Z, Souček O. Diagnosing osteoporosis in children. Osteologický bulletin. 2009;14(2):41-48.
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