Osteologický bulletin, 2007 (vol. 12), issue 1

EditorialEditorial

M. Bayer, ©. Kutílek

Clin Osteol 2007; 12(1): 3

Kyphoplasty and vertebroplasty in the treatment of osteoporotic vertebral fracturesReview articles

P. Pilát, P. Neckafi, M. Sauer

Clin Osteol 2007; 12(1): 4-9

Purpose of the work: Vertebro and kyphoplasty [VP, KP] is a new method, which is used in the treatment of the osteoporotic verteb­ ral fractures. It's relatively simple and safe technique, which brings almost immediate loss of pain and the possibility of early patients mobilization. Purpose of the work was to compare the effec time of analgetic effect and summing up the complications. Material and procedure: From 4/2003 to 2/2006 we made VP and KP on 38 patients, most often was damaged the L1 and the Th12. According to Magerles classification were identified t [VAS] for evaluation of the operated patient's status. Results: Complete number of operated...

Genetic research in osteoporosis: perspectives and experimental basesReview articles

R. Omelka, M. Martiniaková, I. ®ofková

Clin Osteol 2007; 12(1): 11-16

Promising agents for treating osteoporosisGuidelines

S. Kutílek, T. Hála T.

Clin Osteol 2007; 12(1): 17-20

Osteoporosis therapy is closely linked to basic research and development of new antiosteoporotic drugs is a very dynamic process. There are great expectations regarding denosumab (AMG 162), which is a human monoclonal antibody to RANKL. Denosumab is very potent in decreasing bone resorption. Another future antiosteoporotic drug seems to be glucagon-like-peptide-2 (GLP-2), which has proven a strong antiresorptive efficacy. Its effect on bone mineral density and fracture rate needs to be evaluated in further clini­ cal trials. Cathepsin K inhibitors are likely to be another group of perspective drugs to treat osteoporosis. Cathepsin K inhibitors have...

Recommended procedures for diagnosing and treating postmenopausal osteoporosis II. PART ONEGuidelines

J. Rosa

Clin Osteol 2007; 12(1): 24-33

Osteoporosis. Recommended diagnostic and therapeutic procedures for general practitioners. 2006Informations

J. Blahoą, V. Palička, S. Býma

Clin Osteol 2007; 12(1): 35-38

Osteology Centre, Regional Hospital PardubiceInformations

T. Hála

Clin Osteol 2007; 12(1): 39

Zlín 2006 Working DayInformations

Clin Osteol 2007; 12(1): 40

News from around the worldLiterature

Clin Osteol 2007; 12(1): 41-44
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