Clin Osteol 2014; 19(4): 103-109

Effect of creatine on the bone metabolic turnover and quality of bone tissue in ratsOriginal contributions

P. ®ivný, H. ®ivná, K. ©vejkovská, S. Fekete, M. Holeček

Keywords: kreatin, kostní markéry, hustota kostního minerálu, biomechanické testování v SUMMARY ®ivný P in rats

Published: December 11, 2014  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
®ivný P, ®ivná H, ©vejkovská K, Fekete S, Holeček M. Effect of creatine on the bone metabolic turnover and quality of bone tissue in rats. Osteologický bulletin. 2014;19(4):103-109.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Wyss M, Kaddura 2000;80:1107-1213.
    2. Friedecký D, Hlídková E, Novotný D et al. Kreatinin - biochemie, Metaboli a dědičné metabolické poruchy, Laboratorní technologie, web2.stapro.cz/bullfons/42007/labo2.pdf
    3. Gerber I, Gwynn I, Alini M et al. Stimulatory effects of creatine on metabolic ac­ tivity, differentiation and mineralization of primary osteoblast-like cells in mo layer and micromass cell cultures. Eur Cell Mater 2005;10:8-22. Go to original source...
    4. Smith SA, Montain SJ, Matott RP et al. Creatine supplementation and age influ­ ence muscle metabolism during exercise. J Appl Physiol 1998;85:1349-1356. Go to original source...
    5. Larsen RG, Callahan DM, Foulis SA et al. Age-related changes in oxidative capa­ city differ between locomotory muscles and are a behavior. Appl Physiol Nutr Metab 2012;37:88-99. Go to original source...
    6. Stout JR, Sue Graves B, Cramer JT et al. Effects of creatine supplementation the onset of neuromuscular fatigue threshold and muscle strength in elderly men and women (64 - 86 years). J Nutr Health Aging 2007;11:459-464.
    7. Louis M, Lebacq J, Poortmans JR et al. Beneficial effects of creatine supple tation in dystrophic patients. Muscle Nerve 2003;27:604-610. Go to original source...
    8. Wallimann T, Tokarska-Schlattner M, Schlattner U. The creatine kinase system and pleiotropic effects of creatine. Amino Acids 2011;40:1271-1296. Go to original source...
    9. Wallimann T, Wyss M, Brdiczka D et al. Intracellular compartmentation, structu­ re and function of creatine kinase isoenzymes in tissues with high and fluctua energy demands: the 'phosphocreatine circuit' for cellular energy homeostasis. Biochem J 1992;281:21-40. Go to original source...
    10. Dos Santos FS, da Silva LA, Pochapski JA et al. Effects of l-arginine and creat administration on spatial memory in rats subjected to a chronic variable stress mo­ del. Pharm Biol 2014;52:1033-1038. Go to original source...
    11. Brown JP, Albert C, Nassar BA et al. Bone turnover markers in the management of postmenopausal osteoporosis. Clin Biochem 2009;42:929-942. Go to original source...
    12. Lee AJ, Hodges S, Eastell R. Measurement of osteocalcin. Ann Clin Biochem 2000;37:432-446. Go to original source...
    13. Garnero P, Vergnaud P, Hoyle N. Evaluation of a fully automated serum assay for total N-terminal propeptide of type I collagen in postmenopausal osteoporosis. Clin Chem 2008;54:188-196. Go to original source...
    14. Herrmann M, Seidel MJ. The amino- and carboxyterminal cross-linked telopeptides of collagen type I, NTX-I and CTX-I: a comparative review. Clin Chim Acta 2008;393:57-75. Go to original source...
    15. Jadhav SB, Jain GK. Statins and osteoporosis: new role for old drugs. J Pharm Pharmacol 2006;58:3-18. Go to original source...
    16. Swarthout JT, D'Alonzo RC, Selvamurugan N, Prtridge NC. Parathyroid hormo­ ne-dependent signaling pathways regulating genes in bone cells. Gene 2002; 282:1-17. Go to original source...
    17. Gradosova I, Zivna H, Svejkovska K, Palicka V, Tichy A, Zivny P. The role of at vastatin in bone metabolism in male albino Wistar rats. Pharmazie 2011;66(8): 606-610.
    18. ®ivný P, ©vejkovská K, Gradoąová I et al. Moľnosti určení mechanické odolnosti kosti v exprimentu - souhrn poznatků. Osteologický bulletin 2011;16:132-136.
    19. Chrusch MJ, Chilibeck PD, Chad KE et al. Creatine supplementation combined with resistance training in older men. Med Sci Sports Exerc 2001;33:2111-2117. Go to original source...
    20. Gotshalk LA, Kraemer WJ, Mendonca MA et al. Creatine supplementation im­ proves muscular performance in older women. Eur J Appl Physiol 2008;102: 223-231. Go to original source...
    21. Rawson ES, Clarkson PM. Acute creatine supplementation in older men. Int J Sports Med 2000;21:71-75. Go to original source...
    22. Rawson ES, Wehnert ML, Clarkson PM. Effects of 30 days of creatine ingestion in older men. Eur J Appl Physiol Occup Physiol 1999;80:139-144. Go to original source...
    23. Stout JR, Sue Graves B, Cramer JT et al. Effects of creatine supplementation on the onset of neuromuscular fatigue threshold and muscle strength in elderly men and women (64 - 86 years). J Nutr Health Aging 2007;11:459-464.
    24. Candow DG, Little JP, Chilibeck PD et al. Low-dose creatine combined with pro­ tein during resistance training in older men. Med Sci Sports Exerc 2008;40: 1645-1652. Go to original source...
    25. Crepaldi G, Maggi S. Sarcopenia and osteoporosis: A hazardous duet. J Endo­ crinol Invest 2005;28, Suppl 10:66-68.
    26. Clegg A, Young J, Iliffe S et al. Frailty in elderly people. Lancet 2013;381: 752-762. Go to original source...
    27. Candow DG, Chilibeck PD. Potential of creatine supplementation for improving aging bone health. J Nutr Health Aging 2010;14:149-153. Go to original source...
    28. Candow DG, Chilibeck PD, Forbes SC. Creatine sculoskeletal health. Endocrine 2014;45:354-361. Go to original source...
    29. Louis M, Poortmans JR, Francaux M et al. No effect of creatine supplementation on human myofibrillar and sarcoplasmic protein synthesis after resistance exe se. Am J Physiol Endocrinol Metab 2003;285:E1089-1094. Go to original source...
    30. Tarnopolsky MA, Mahoney DJ, Vajsar J et al. Creatine monohydrate enhances strength and body composition in Duchenne muscular dystrophy. Neurology 2004; 62:1771-1777. Go to original source...
    31. Chilibeck PD, Chrusch MJ, Chad KE et al. Creatine monohydrate and resistance training increase bon Aging 2005;9:352-353.
    32. de Souza RA, Xavier M, da Silva FF et al. Influence of creatine supplement on bone quality in the ovariectomized rat model: an FT-Raman spectroscopy stu­ dy. Lasers Med Sci 2012;27:487^95. Go to original source...
    33. Cornish SM, Candow DG, Jantz NT et al. Conjugated linoleic acid combined with creatine monohydrate and whey protein suppleme Int J Sport Nutr Exerc Metab 2009;19(1):79-96. Go to original source...
    34. Deldicque L, Louis M, Theisen D et al. Increased IGF mRNA in human skele muscle after creatine supplementation. Med Sci Sports Exerc 2005;37:731-736. Go to original source...
    35. Funanage VL, Carango P, Shapiro IM et al. Creatine kinase activity is required mineral deposition and matrix synthesis in endochondral growth cartilage. Bone Miner 1992;17:228-236. Go to original source...
    36. Antolic A, Roy BD, Tarnopolsky MA et al. Creatine monohydrate increases bone mineral density in young Sprague-Dawley rats. Med Sci Sports Exerc 2007;39: 816-820. Go to original source...
    37. Beck TJ, Kohlmeier LA, Petit MA et al. Confounders in the association between exercise and femur bone in postmenopausal women. Med Sci Sports Exerc 2011;43: 80-89. Go to original source...
    38. Bemben MG, Witten MS, Carter JM et al. The effects of supplementation with creatine and protein on muscle strength following a traditional resistance training program in middle-aged and older men. J Nutr Health Aging 2010;14:155-159. Go to original source...
    39. Bermon S, Venembre P, Sachet C et al. Effects of creatine monohydrate ingestion in sedentary and weight-trained older adults. Acta Physiol Scand 1998;164: 147-155. Go to original source...
    40. Eijnde BO, Van Leemputte M, Goris M et al. Effects of creatine supplementation and exercise training on fitness in men 55-75 year old. J Appl Physiol 2003;95: 818-828. Go to original source...
    41. Eliot KA, Knehans AW, Bemben DA et al. The effects of creatine and whey pro­ tein supplementation on body composition in men aged 48 to 72 years during re­ sistance training. J Nutr Health Aging 2008;12:208-212. Go to original source...
    42. Alves CR, Murai IH, Ramona P et al. Influence of creatine supplementation on bone mass of spontaneously hypertensive rats. Rev Bras Reumatol 2012;52: 453-461.
    43. Kim HJ, Kim CK, Carpentier A et al. Studies on the safety of creatine supple­ mentation. Amino Acids 2011;40:1409-1418. Go to original source...

    Return to the content


    Clinical Osteology

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.