Clin Osteol 2014; 19(1): 23-27

Periodontal bone response under the influence of Cr(VI)Original contributions

Y. Kuzenko, A. Romanyuk, A. Korobchanskaya, L. Karpenko

Object: The object of this study has analyzed alveolar bone reponse under the influence chromium (VI).

Methods: 20 male albino rats (300-325 g) have been evaluated for histological and scanning electron microscopy of Ca, P, K, Cr.

Results: The interaction between normal periodontal tissues and 60 days experiment was strongly significant. Destruction may progress until tooth support becomes inadequate and more complex patterns of bone loss develop. Despite the deep extension of in­ flammation it may be absent in the alveolar bone, which may also lack any sign of osteoclastic activity histologically. The lowest levels of P and K were observed in 60 days of experiment (P < 0.01). 60 days level may affect the mineral status of bone and chronic inco­ ming of chromium.

Conclusion: Chronic chrome (VI) intoxication is characterized by severe chronic destruction of collagen, apoptotic, bone changes, and epithelial hyperplasia. Untreated chronic chrome (VI) intoxication slowly progresses to chronic periodontitis in which the de­ struction of deep tissues develops. Within 60 days, progressive resorption of alveolar bone occurs and the tooth ultimately gets deta­ ched.

Keywords: chromium, male albino rats, periodontal bone response

Published: June 11, 2014  Show citation

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Kuzenko Y, Romanyuk A, Korobchanskaya A, Karpenko L. Periodontal bone response under the influence of Cr(VI). Osteologický bulletin. 2014;19(1):23-27.
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