Clin Osteol 2013; 18(2): 44-47
Comparison of fracture risk in postmenopausal women in Slovakia and the neighboring countriesOriginal contributions
More than half of fragility fractures occur in patients with osteopenia and effort is given to identifying these high-risk patients. For this purpose, the FRAX tool was developed that calculates absolute 10-year fracture risks. The FRAX is calibrated to epidemiological da ta of each country. If it is not available for a specific country, the use of a surrogate country model with similar epidemiological data is recommended. Variability among several countries can lead to significant differences in patient counts in treatment initiation. Aim of the study: To compare the proportion of patients indicated for antiosteop with the Slovak version of FRAX and FRAX versions for the neighboring countries.
Patients and methods: Fracture risk was assessed in 152 postmenopausal women with the Slovak version of FRAX and FRAX versions for the neighboring countries. The numbers of patients indicated for antiosteoporotic treatment were compared according to the National Osteoporosis Foundation criteria (> 20 % for major osteoporotic fracture or > 3 % for hip fracture).
Results: There was a statistically significant difference in the proportion of patients indicated for treatment according to fracture risks assessed with the Slovak FRAX and the Hungarian, Polish and Czech FRAX versions. The difference between the proportion of pa tients indicated for treatment according to fracture risks assessed with the Slovak and Austrian FRAX was not significant.
Conclusion: When assessing fracture risk with the FRAX and indicating treatment, it is necessary to use the FRAX calibrated to epi demiological data of the given country Vari indicated for antiosteoporotic treatment.
Keywords: FRAX, fracture risk, osteoporosis
Published: December 11, 2013 Show citation
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